Thursday, March 7, 2013

Bin Laden son-in-law caught in Jordan

WASHINGTON (AP) ? Osama bin Laden's spokesman and son-in-law has been captured by the United States, officials said Thursday, in what a senior congressman called a "very significant victory" in the ongoing fight against al-Qaida.

Abu Ghaith is expected to be in U.S. federal court in New York on Friday in an initial hearing to face terror charges, according to a law enforcement official who spoke on condition of anonymity because he was not authorized to release the information.

Rep. Peter King, the former chairman of the House Homeland Security Committee, credited the CIA and FBI with catching al-Qaida propagandist Sulaiman Abu Ghaith in Jordan within the last week. He said the capture was confirmed to him by U.S. law enforcement officials.

A Jordanian security official confirmed that al-Ghaith was handed over last week to U.S. law enforcement officials under both nations' extradition treaty. He declined to disclose other details and spoke on condition of anonymity because of the sensitivity of the matter.

"Definitely, one by one, we are getting the top echelons of al-Qaida," said King, R-N.Y. "I give the (Obama) administration credit for this: it's steady and it's unrelenting and it's very successful."

Abu Ghaith became an international name in late 2001 when he appeared on pan-Arab satellite television urging Muslims everywhere to fight the United States and warning of more attacks similar to those of Sept. 11. In one video, he was sitting with bin Laden in front of a rock face in Afghanistan. A teacher and mosque preacher in Kuwait, he was stripped of his Kuwaiti citizenship after 9/11.

He is identified as a major al-Qaida core official by the New America Foundation think tank in Washington. King said Abu Ghaith was involved in the planning in the 9/11 attacks against the World Trade Center and Pentagon.

Tom Lynch, a research fellow at the National Defense University in Washington, described Abu Ghaith as one of a small handful of senior al-Qaida leaders "capable of getting the old band back together and postured for a round of real serious international terror."

"His capture and extradition not only allows the U.S. to hold ? and perhaps try ? a reputed al-Qaida core survivor, further tarnishing the AQ core brand, but it also points to the dangers for those few remaining al-Qaida core refugees," Lynch said.

The Turkish newspaper Hurriyet reported that Abu Ghaith was caught while passing through Jordan, on his way to Kuwait, shortly after leaving Turkey.

The newspaper said that Abu Ghaith was taken into custody more than a month ago at a luxury hotel in in Ankara, the Turkish capital. But Turkish officials decided he had not committed any crime in Turkey and released him, the newspaper reported.

In Ankara, Turkish officials refused to confirm Abu Ghaith's deportation or his capture in Jordan to The Associated Press. In Amman, the Jordanian capital, a security official said he had no information on the CIA arrest in Jordan.

U.S. intelligence officials in Washington and New York refused to comment on the case.

___

Associated Press writer Tom Hayes in New York and Jamal Halaby in Amman, Jordan, contributed to this report.

___

Follow Lara Jakes on Twitter at: https://twitter.com/larajakesAP

Source: http://news.yahoo.com/us-official-bin-laden-spokesman-caught-jordan-153446737.html

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Study pinpoints, prevents stress-induced drug relapse in rats

Mar. 6, 2013 ? In a new study in Neuron, scientists identified specific key steps in the chain of events that causes stress-related drug relapse. They identified the exact region of the brain where the events take place in rat models and showed that by blocking a step, they could prevent stress-related relapse.

"We're at the point of coming to understand the processes (of stress-related drug relapse) and possible therapeutic targets. Remarkably, this has worked. All too often, stress turns addiction recovery into relapse, but years of basic brain research have provided scientists with insight that might allow them develop a medicine to help. A new study in the journal Neuron pinpoints the neural basis for stress-related relapse in rat models to an unprecedented degree. The advance could accelerate progress toward a medicine that prevents stress from undermining addiction recovery.

In the paper published March 6, researchers at Brown University and the University of Pennsylvania demonstrated specific steps in the sequence of neural events underlying stress-related drug relapse and showed that they take place within a brain region called the ventral tegmental area (VTA), which helps reinforce behaviors related to fulfilling basic needs. They also showed that a closely related neural process believed to be crucial to stress-related relapse may not be involved after all.

Moreover, this new understanding allowed the researchers to prevent relapse to drug seeking in the animal model. When they treated rats that had recovered from cocaine addiction with a chemical that blocks the "kappa opioid receptors" that stress activates in the VTA, the rats did not relapse to cocaine use under stress. Untreated rats who had also recovered from addiction did relapse after the same stress.

The chemical that helped the rats, "nor-BNI," may be one that would someday be tried in humans, said study senior author Julie Kauer, professor of biology in Brown's Department of Molecular Pharmacology, Physiology, and Biotechnology. By deepening scientists' understanding of the stress-related relapse mechanism, she and her co-authors hope to identify multiple possible targets for eventual patient treatments.

"If we understand how kappa opioid receptor antagonists are interfering with the reinstatement of drug seeking we can target that process," Kauer said. "We're at the point of coming to understand the processes and possible therapeutic targets. Remarkably, this has worked."

The neural crux of relapse

Exactly how stress acts in the brain to trigger relapse is a complicated sequence that is still not fully understood, but the new study focuses on and elucidates three key players at the crux of the phenomenon in the VTA: GABA-releasing neurons, dopamine-releasing neurons, and the kappa opioid receptors that affect their connections.

Fulfilling natural needs such as hunger or thirst results in a rewarding release of dopamine from the VTA's dopamine neurons, Kauer said. Unfortunately, so does using drugs of abuse.

In normal brain function, GABA applies the brakes on the rewarding dopamine release, slowing it back to a normal level. It achieves this by forging and then strengthening the connections, called synapses, with the dopamine neuron. The strengthening process is called long-term potentiation (LTP).

In the first of their experiments, the team at Brown, including lead author Nicholas Graziane, showed that stress interrupts the LTP process, hindering GABA's ability to slam the brakes on dopamine release.

Previous research implicated kappa opioid receptors as one of many neural entities that could have a role in stress-related relapse. Kauer, Graziane, and co-author Abigail Polter investigated that directly by blocking the receptors in some rats with a treatment of nor-BNI in the VTA and leaving others untreated. Then they subjected the rats to a standardized five-minute stress exercise. After 24 hours they looked at the cells in the VTA and found that LTP was hindered in the untreated rats but still present and underway in the rats whose receptors had been blocked with nor-BNI.

With the role of stress and the receptors in the GABA-dopamine dynamic both confirmed and then mitigated, the question remained: Could this knowledge be used to prevent relapse?

To answer that, Penn co-authors Lisa Briand and Christopher Pierce performed the experiment demonstrating that nor-BNI delivered directly to the VTA prevented stressed rats from relapsing to cocaine seeking, while untreated rats subjected to the same stress did relapse.

"Our results indicate that the kappa receptors within the VTA critically control stress-induced drug seeking in animals," the authors wrote in Neuron.

Along the way, the team also discovered evidence that another stress-affected synapse in the VTA -- one that excites dopamine release rather than inhibits it -- does not play a role in the stress-related relapse as many researchers have thought. The nor-BNI treatment that prevented stress-related relapse, for example, did not affect those synapses.

Kauer emphasized that her lab's findings of therapeutic potential are the product of more than a decade of essential basic research on the importance of how changes in synapses relate to behaviors including addiction.

"If we can figure out how not only stress, but the whole system works, then we'll potentially have a way to tune it down in a person who needs that," she said.

The National Institutes of Health supported the research with several grants: DA011289, MH019118, AA007459, DA026660, DA15214, and DA18678.

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The above story is reprinted from materials provided by Brown University.

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Journal Reference:

  1. Nicholas M. Graziane, Abigail M. Polter, Lisa A. Briand, R. Christopher Pierce, Julie A. Kauer. Kappa Opioid Receptors Regulate Stress-Induced Cocaine Seeking and Synaptic Plasticity. Neuron, 2013 DOI: 10.1016/j.neuron.2012.12.034

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/~3/i0W3oXTdNSo/130306134220.htm

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Monday, March 4, 2013

Baptism of Uzi secures grant | Surf Coast Times ? Bellarine Times ...

At a time when Victorian musician and triple Grammy winner Gotye has focused the eyes of the world on Victorian music, local group Baptism of Uzi from East Geelong has the chance to follow in his footsteps thanks to the Victorian Government?s Contemporary and Live Music Development program.

Member for Western Victoria David Koch congratulated Thomas Battersby and Baptism of Uzi on receiving a grant that will give support to developing the group?s career in the music business.

?This grant of $6,228 will be a great boost for heavy rock outfit Baptism of Uzi and will go a long way towards the production and promotion of their debut album,? he said.

Premier and Minister for the Arts Ted Baillieu said the Contemporary and Live Music Development program, through Arts Victoria, supported all genres of contemporary music and supported musicians at a range of different career stages.

?This program aims to support the creative growth and viability of the Victorian music industry, to help musicians find a voice and to be heard by audiences across the state, the country and the globe.

?Artists who have previously received support through the program include Paul Dempsey, Claire Bowditch and last week?s big winner Gotye, who received a music touring grant in 2008 to support a European tour to promote his second album.

?That tour helped him get in front of international audiences and it has been fantastic to see his career skyrocket since then.?

The next round of the Contemporary and Live Music Development program closes on Tuesday 12 March 2013. Funds are available in three categories: career building, music touring and sector development.

To see a full list of this round?s recipients, visit arts.vic.gov.au/news.

Source: http://www.surfcoasttimes.com.au/entertainment/music/2013/03/03/baptism-of-uzi-secures-grant/

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Sunday, March 3, 2013

iMore Editors' Choice: Star Wars pinball, Instashare, Weathercube, and more

Every week, the editors and writers at iMore carefully select some of our favorite, most useful, most extraordinary apps, accessories, gadgets, and websites. This week's selections include an app that lets you share files from your iPhone or iPad to your Mac, a movie app, some killer bluetooth headphones, a Pinball game featuring Star Wars, a really cool weather app, and a shopping app for mom's with tons of great deals.

Instashare - Joseph Keller

I?m always looking for a better way to get files from my iOS devices to my Mac, and vice versa. For photos and screenshots, I have to wait for iPhoto to open, then either connect my device via cable or wait for it to come through Photostream. For documents, it?s a little easier, just having to wait for iCloud or Dropbox to sync. But I?ve been looking for something better, and Instashare is it. Instashare is like AirDrop for iOS. You can move files between Macs and iOS devices instantly.

To use Instashare, simply download the app, then download the desktop app, currently in beta for Mac only. To move something from your Mac to an iOS device, simply drag the file you wish to move up to the menubar icon, then, when the dropdown appears, drag the file to the desired device. A similar process is used on iOS, where you drag the file you want onto the available Mac.

There are some downsides. First, while iOS allows apps to access your photo albums, no such permissions are given to your documents, so documents can only be transferred from a Mac to an iOS device. Second, for now, it?s Mac only, but apps for Android and Windows are currently in development. Instashare is a free universal download, with a $0.99 in-app purchase to remove ads.

Spideo Instant Movie Discovery - Chris Parsons

Like a lot of folks these days, I don't have much time to get up-to-date with all the latest movie releases happening and well, quite honestly I really don't want to try. I find a lot of movies released these days quite boring so to help me weed out some of the good from the bad I often turn to Spideo Instant Movie Discovery. Rather than spending time looking through movies, being indecisive about what I want to watch and ultimately just giving up altogether, I just tell Spideo how I'm feeling and a general idea of my mood. It goes out, finds some movies and lets me view all the details of it as well, view the trailer. It also works with TV shows but I've never really used that function. Now, while I find Spideo great for offering up choices, it's still up to you to actually go out and find the content if it's outside of iTunes.

Plantronics BackBeat 903+ - Chris

This week I have really stepped up my gym activities s and decided that I needed some Bluetooth headphones. I was sick of running and catching the cable on the wired set that I have so I went on the hunt for a good set of Bluetooth headphones.

My research kept bringing me back to the Plantronics BackBeat 903+ which received some great reviews based on sound quality, battery life and how comfortable they were to wear for long periods. I took the plunge and ordered a pair and I haven?t been disappointed.

The sound quality is really great, not as bass heavy as my Bose wired set but not that far away either, The sound is very clear and the actual headset is extremely comfortable to wear too. Controls on each earpiece allow you to remotely turn the volume up and down, play and pause music and skip tracks.

I am really impressed with the Plantronics BackBeat 903+ Bluetooth headphones and can highly recommend them; the freedom they give you just by no longer needing wires is very liberating. The battery life seems excellent too, I still have over 5 hours left and I have used them for at least 3 hours since I charged them.

Zen Pinball's Star Wars Pinball - Rene Ritchie

Zen Pinball has a great thing going. They have a pretty darn good pinball game engine to start with, but they also have killer licenses. Last year it was X-Men, Avengers, and a half-dozen similarly colossal marvel comic book tables. This year it's Star Wars, starting with The Empire Strikes Back, Boba Fett, and the Clone Wars.

The play is classic pinball gone digital, but because it's digital, they can include little mini-games as well. I'm not someone who spend hours flipping paddles and lighting up every inch of a table, but for those brief moments when I just want to unwind and have fun, Zen Pinball and their new Star Wars tables take me right back to the arcade.

Best of all, they don't nickel-and-dime -- or quarter! -- you for every in-app purchase imaginable. The game is free to download and you get one basic table. Additional tables are $1.99 and that's it.

If you're a fan of classic pinball action or just love everything Star Wars -- or Marvel -- check it Zen Pinball and their new Star Wars Pinball tables.

Weathercube - Ally Kazmucha

I have an obsession with weather apps both on the iPhone and on the iPad. I don't know what it is. I either get bored or feel the need to check the forecast on a few different apps and see how they match up.

I stumbled upon Weathercube the other day and it's definitely an interesting take on the weather. You're basically given a cube that you can rotate around to see different aspects of the weather in different areas. Weathercube is completely gesture driven so there aren't a lot of menus to go around tapping through. If you've ever used Clear for iPhone, you'll notice a lot of similarities gesture wise.

Weathercube may not be as full featured at some of the other guys, but it's a gorgeous app and definitely a wildly different approach when it comes to viewing weather info. Weathercube is currently free in the App Store to celebrate being the app of the week so snag it while you can. Regular price is $0.99.

Zulily - Leanna Lofte

A friend recently told me about zulily, a shopping app with daily deals, and the first thing I did was search for an iPhone app. Not only is zulily a totally awesome and addicting shopping service with tons of adorable stuff for kids and moms, but their app is also very well made. If you're unfamiliar with zulily, it features daily deals for moms, babies, and kids with boutique and designer brands that are up to 90% off. With the zulily app, you can set alarms to remind you when something you've been keeping your eye on becomes available so that you can grab it before it sells out. I love this service, and I love this app.

Your choice?

Now that we've chosen our favorites for the week, we want to hear yours! Did you pick up a killer app, accessory, or game this week? Let us know in the comments below!



Source: http://feedproxy.google.com/~r/TheIphoneBlog/~3/QAwdXjZ6t64/story01.htm

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George Heymont: When Musicals Reflect Our Lives

Musicals are one of America's most beloved forms of entertainment. Audiences have been cheering tap dancing ensembles, dream ballets, rousing choruses, and witty comedic numbers since the 1866 Broadway premiere of The Black Crook. Musicals have often offered audiences a chance to explore controversial topics of the day.

Based on the novel by Edna Ferber, 1927's Show Boat dealt with the topic of miscegenation. In 1933's As Thousands Cheer, Ethel Waters shocked audiences with Irving Berlin's poignant "Supper Time," a song about a woman whose husband has just been lynched (As Thousands Cheer was also the first Broadway show to give an African American star equal billing with the white performers headlining its cast).


While most of the kudos for Rodgers and Hammerstein's 1949 hit, South Pacific, were showered upon Mary Martin, Ezio Pinza, Myron McCormick, and Juanita Hall, it was William Tabbert (as the handsome, young Lieutenant Joseph Cable) who sang "You've Got To Be Carefully Taught." This song was considered indecent, pro-Communist, and inspired one legislator to label its justification of interracial marriage as "a threat to the American way of life." According to to Wikipedia, while South Pacific was touring Southern cities, lawmakers in the state of Georgia introduced a bill outlawing any entertainment containing "an underlying philosophy inspired by Moscow."


In 1983, La Cage aux Folles (written by Jerry Herman and Harvey Fierstein) melted the hearts of countless heterosexuals just a few short years after Anita Bryant and the religious right had begun scapegoating the LGBT community. In 1992, James Lapine and William Finn brought the AIDS epidemic to the musical stage with Falsettos. In the following clip, Michael Rupert sings the heartrending "What More Can I Say?"


In the past 25 years, musical theatre has often aimed for cultural relevancy.

  • In 1990, Sondheim and Weidman reunited for Assassins, a show about Presidential killers.
  • In 1996, Jonathan Larson's prize-winning musical, Rent, was an updated version of Puccini's La Boh?me whose protagonists were surrounded by the AIDS crisis.
  • In 1998, Ragtime (a musical adaptation of E. L. Doctorow's novel) examined the struggles of three different socioeconomic groups (whites, immigrant Jews, and African Americans) in the early 20th century.
  • In 2001, Urinetown lampooned capitalism, political corruption, bureaucratic rot, and urban decay.
  • Hairspray (a popular 1988 John Waters comedy about racial integration) was transformed into a 2002 musical starring Harvey Fierstein as Edna Turnblad.
  • In 2004, Caroline or Change focused on a black maid working for a Jewish family in Lake Charles, Louisiana at the time of President Kennedy's assassination.
  • In 2009, a married woman's struggle with bipolar disorder became the inspiration for Next To Normal

.

In 2007, the Marsh Youth Theatre in San Francisco created Siddhartha, The Bright Path (which was revived in December of 2010). There's a new Buddha figure in town (a female version) as the protagonist of an impressive new musical being performed at the Ashby Stage in Berkeley through March 10.

The Fourth Messenger is much more than a pleasant surprise. This is an intelligent, skillfully crafted, and extremely ambitious piece of music theatre about spirituality and self discovery that demands the attention of any serious theatregoer or student of religion.

2013-02-19-messengerposter.jpg

Poster art for The Fourth Messenger


Written by Tanya Shaffer (whose Baby Taj delighted TheatreWorks audiences at its world premiere in October of 2005), The Fourth Messenger is far from a formula musical. As Shaffer explains:

"For years I've been drawn to the legend of Siddhartha Gautama (it's such a mythic, archetypal journey) but I knew I had to find my own way into the story. It wasn't going to be some historical pageant. It had to be urgent, contemporary, and immediate. Buddha's teachings are profound, poetic, and timeless but there were elements of his life which a modern audience might find troubling. Those elements -- the moral questions and conundrums -- became my way into this ancient story and provide the juice that drives the narrative forward.

A lengthier rehearsal period also allows the actors to find a lot more subtlety and nuance within their choices. After years of concert-style readings, it's quite a revelation to see the transformation that takes place when a scene is fully staged. Sometimes, after a public reading, audience members would say to me that they saw it all in their heads; they didn't miss the other theatrical elements at all. At the time, I felt that too. But now, as the scenes come to life before my eyes, I find them infinitely richer than they've ever been. The comic scenes are much funnier when they are fully physicalized. The poignant moments, too, are infinitely more moving when the actors are able to fully embody their characters, so that their reactions and choices are transmitted through action and gesture as well as face and voice."

2013-02-19-angelsid.jpg
Annemaria Rajala as Mama Sid (Photo by: Mike Padua)


Driven by Vienna Teng's densely-written lyrics and propulsive score, The Fourth Messenger opens in a tense newsroom where a publisher (Will Springhorn, Jr.) is facing diminished ad revenues. As his editorial staff hungers for a big news story to debunk, his lover Raina (Anna Ishida) returns from her father's funeral.

Although she's pretty torn up over the loss of her Dad, Raina also thinks she might have found the story that will save Sam's business ("The Next Big Story"). When Sam reflexively assigns it to a young male reporter, she calls him on it and demands that he let her interview the latest trendy guru, a mysterious woman named Mama Sid (Annemarie Rajala) whom Raina suspects is a fraud.

When Raina arrives at Mama Sid's ashram, she thinks Sid's trusting, emotionally needy followers are either brainwashed or crazy. As they wrestle with their compulsions and obsessions ("Monkey Mind"), Raina finally gets a chance to interview Sid, who sings of "The Human Experience" and begins to open up about her previous experiences. For some reason, Sid feels compelled to divulge her past to Raina, starting with her youthful crush on Yasha (Barnaby James) and the sheltered existence she enjoyed while being raised in a gated community ("Bois Riche").

As Sid describes her traumatic exposure to poverty and disease outside Bois Riche, her story deepens and takes numerous unexpected turns. By the time the audience learns that Sid is actually Raina's mother (who abandoned Raina shortly after she was born in order to seek her own path in life), Shaffer's musical has the audience emotionally involved in the story and, often, on the edge of their seats.

2013-02-19-sidraina.jpg
Mama Sid (Annemarie Rajala) and Raina (Anna Ishida) in
The Fourth Messenger (Photo by: David Allen)


Much has been written in recent years about the growth of online crowd funding services. Last year, Kickstarter boasted that it had raised $150 million for creative projects (more than 2012's operating budget for the National Endowment for the Arts). Songwriter Jeff Bowen ([title of show]) launched a Kickstarter campaign to raise the $75,000 he needed to record a cast album of his recent off-Broadway musical Now. Here. This. The happy result? Bowen's Kickstarter campaign brought in $89,833!

In addition to money raised through traditional approaches, Shaffer and Teng brought in almost $40,000 through a crowd-funding campaign on Indiegogo. As the producer/playwright explains:

"We live in a time when it's more feasible than ever for artists to take matters into their own hands. The decision for Vienna and me to produce this ourselves came about organically. Talking with theaters, we encountered reluctance to even consider a world premiere musical that required a minimum of nine actors and four musicians in the current economic climate. After a few of those conversations, we came to this Little Red Hen moment of 'I'll do it myself.' The response from supporters was immediate, enthusiastic, and truly empowering."
2013-02-19-sidandy.png
Sid (Annemarie Rajala) with her close friend, Andy (Jackson Davis) in
The Fourth Messenger (Photo by: Matt August)


Even in a show about Buddhism, money buys artistic freedom. The results were obvious at the world premiere of The Fourth Messenger (which is so much more than a labor of love). Joe Ragey has created a simple yet remarkably elegant unit set which allows for quick and highly effective transitions between scenes. The orchestrations by Robin Reynolds are first rate and, under Christopher Winslow's solid musical direction, Teng's music and lyrics reveal a fresh and exciting new theatrical talent with a distinctive voice of her own (click here to listen to excerpts from the show's musical score).

Above all, The Fourth Messenger has been beautifully staged with grace, wit, and plenty of dramatic flair by Matt August (who staged Shaffer's Baby Taj and pulls exceptionally poignant performances from his two female leads). Jackson Davis has some fine dramatic moments as Sid's close friend, Andy. Cathleen Riddley, Will Springhorn, Jr., Reggie D. White, Simeone Kertesz, and Barnaby Jones all score strongly in supporting roles.

The Fourth Messenger is a hugely ambitious and refreshingly original piece of musical theatre that is highly recommended. Accessible to contemporary audiences and relevant to today's search for spirituality, I wish it a long and healthy future enchanting audiences around the world. Here's the trailer:


To read more of George Heymont go to My Cultural Landscape

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Follow George Heymont on Twitter: www.twitter.com/geoheymont

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Source: http://www.huffingtonpost.com/george-heymont/when-musicals-reflect-our_b_2800096.html

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